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L-glutamic acid    98%

L-glutamic acid is an important neurotransmitter and amino acid, which plays a complex and key role in the nervous system. As a precursor of neurotransmitters, L-glutamic acid promotes the excitement of neurons by participating in the transmission of excitatory signals between neurons. This process involves the release of L-glutamate in the synapse and binds to the receptor, triggering nerve signal transmission. In addition, L-glutamic acid regulates glutamic acid balance inside and outside neurons by participating in the reverse amino acid transport process, which is very important for the stability and normal function of neurons. 

L-Tryptophan    98%

L-tryptophan plays a key role in the nervous system, supporting many aspects of information transmission. First of all, as the precursor of neurotransmitters serotonin and melanin, L-tryptophan participates in the regulation of mood, sleep and cognitive function by synthesizing these neurotransmitters, which directly affects the transmission of neural signals. Secondly, L-tryptophan maintains the normal function of nerve cells and indirectly supports the healthy transmission of nerve information by participating in the process of cell energy metabolism and DNA repair. Therefore, adequate L-tryptophan intake not only helps to balance the function of the nervous system, but also provides sufficient support for information transmission.

L-phenylalanine    98%

L-phenylalanine is an amino acid that plays a key role in information transmission. It acts as the raw material for the synthesis of neurotransmitters in the nervous system, which directly affects the transmission of nerve signals by participating in the synthesis of neurotransmitters such as dopamine, epinephrine and norepinephrine. In addition, L-phenylalanine is an important component of protein synthesis, which is very important for cell signal transduction and biological growth and development. L-phenylalanine also plays an important role in the body's immune system, affecting lymphocyte function and immune response. 

GABA-γ-aminobutyric acid    98%

GABA (γ-aminobutyric acid) is a neurotransmitter that plays an important role in information transmission in the central nervous system. As an inhibitory neurotransmitter, GABA binds to the GABA receptor of neurons, which leads to the opening of intracellular ion channels and the influx of chloride ions, thus increasing the negative membrane potential of neurons and inhibiting nerve impulses. This inhibitory effect is very important to balance the excitatory and inhibitory signals in the neural system and maintain the stability of the neural network. 

Saffron extract    10:1

The main active components in saffron include various carboxylated compounds, flavonoids and all kinds of alkaloids. These ingredients endow saffron extract with a variety of pharmacological activities, the most prominent of which is its antioxidant and anti-inflammatory properties. Antioxidation helps to scavenge free radicals and reduce the damage of oxidative stress to cells, thus helping to maintain the normal function of cells. In addition, saffron extract has been shown to have antidepressant and anti-anxiety potential, which may support emotional health by affecting neurotransmitter levels and neurotransmitter receptor activity. In general, saffron extract at 10:1 plays a positive role in information transmission and maintenance of physiological balance through its diversified pharmacological activities, including antioxidation and neuroregulation. 

Nerve regeneration

Pleurotus Citrinopileatus extract Ergothioneine 0.5%-2%

Pleurotus Citrinopileatus extract has a positive effect on nerve regeneration, mainly due to its active ingredients such as polysaccharides and polyphenols. The main functions of polysaccharides in Pleurotus Citrinopileatus include promoting the proliferation and differentiation of neural stem cells and improving the survival rate of neurons. Studies have shown that polysaccharides from Pleurotus Citrinopileatus may promote nerve regeneration by activating related growth factors and pathways, such as nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF). In addition, the polyphenols in the mushroom have significant antioxidant activity, which can help reduce the damage to nerve cells caused by oxidative stress. Oxidative stress is an important factor in the development of many neurological diseases, and the antioxidant properties of Pleurotus Citrinopileatus may help protect nerve cells from oxidative damage and provide support for nerve regeneration. 

Pyrroquinone quinone disodium salt (PQQ) 98%

First, pyrroloquinoline quinone promotes nerve signal conduction by increasing the fluidity of nerve cell membranes and improving the stability of cell membranes. This may help improve the membrane elasticity of neurons and promote normal electrical signal transmission, thereby having a positive effect on nerve regeneration. Secondly, pyrroloquinoline quinone enables brain cells to use energy more efficiently and supports the normal function and regeneration of nerve cells by regulating the metabolic activity of neurons. In addition, pyrroloquinoline quinone has also been considered to potentially promote nerve regeneration by enhancing synaptic plasticity. 

Black garlic extract     S-allyl cysteine 0.03%

S-allylcysteine (SAC), which is contained in the extract of black garlic, plays a neuroprotective role through antioxidation. Its antioxidant properties help to neutralize free radicals, reduce the damage of nerve cells caused by oxidative stress, and provide a favorable environment for nerve regeneration. It can also promote the proliferation and differentiation of neural stem cells by regulating signal pathways such as nerve growth factor (NGF), thus supporting nerve regeneration. 

Kumquat peel extract Nobiletin 5%-30%

Nobiletin in kumquat peel extract, as a potential nerve regeneration active ingredient, can have a positive impact on nerve tissue through multiple pathways such as antioxidant, promoting nerve cell proliferation and differentiation, and regulating inflammation. Its antioxidant properties help reduce oxidative stress damage to nerve cells and promote the survival and regeneration of nerve cells. In addition, nobiletin may support the proliferation and differentiation of neural stem cells and promote nerve regeneration by regulating the nerve growth factor signaling pathway. 

NMN    99%

Niacinamide mononucleotide (NMN) is a compound thought to have potential effects on nerve regeneration. As a precursor of NAD+, it may have positive effects on neural tissue through multiple mechanisms. First, NMN supplementation may increase intracellular NAD+ levels, thereby supporting cellular energy metabolism and circadian clock regulation, and promoting the normal function and regeneration of nerve cells. Secondly, NMN may help slow down cell aging and promote the renewal of nerve cells by activating Sirtuin proteins, a type of protein related to cell longevity and antioxidants. In addition, NMN may also participate in the DNA repair process, reduce the adverse effects of DNA damage on nerve cells, and provide protection for nerve regeneration. 

Nerve cell protection

Pine needle extract10:1

Pine needle extract, especially in a concentrated 10:1 ratio, is thought to have neuroprotective potential. Research suggests that pine needle extract may exert this protective effect through multiple pathways. First, it is rich in antioxidants, such as flavonoids, which may help neutralize free radicals and reduce oxidative stress damage to nerve cells. Secondly, pine needle extract may provide direct protection to nerve cells by inhibiting the process of nerve cell apoptosis (cell self-destruction). In addition, pine needle extract may regulate the release of neurotransmitters and affect signaling between neurons, thereby maintaining the stability of neural networks. 

γ-aminobutyric acid(GABA) 98%

GABA (gamma-aminobutyric acid) is a neurotransmitter that is also thought to have neuroprotective potential. Its mechanism of nerve cell protection involves many aspects. First of all, GABA helps maintain the stable state of neural networks and prevent nerve cell damage caused by over-excitation by regulating the balance of excitability and inhibition between neurons. Secondly, GABA may reduce the negative impact of oxidative stress on nerve cells through its antioxidant effect and provide cell protection. In addition, GABA may reduce excessive intracellular calcium concentration and prevent damage to nerve cells caused by calcium ion toxicity by regulating intracellular calcium ion levels. 

Olive fruit extract Hydroxytyrosol 5%-20%

Olive fruit extract contains hydroxytyrosol, a natural antioxidant that is thought to have neuroprotective effects. Hydroxytyrosol may have positive effects on nerve cells through several mechanisms. First, its powerful antioxidant properties help neutralize free radicals and reduce oxidative stress damage to nerve cells. Secondly, hydroxytyrosol may promote the survival and regeneration of nerve cells by regulating cell signaling pathways, including nerve growth factor (NGF). In addition, hydroxytyrosol may also regulate the release of neurotransmitters and maintain normal communication between neurons, thus contributing to the stability of neural networks. 

Kumquat peel extract Nobiletin 5%-30%

Kumquat peel extract is rich in nobiletin, a natural active ingredient thought to have the potential to protect nerve cells. Nobiletin may have positive effects on nerve cells through a variety of pathways. First, its significant antioxidant properties help neutralize free radicals and reduce oxidative stress damage to nerve cells. Secondly, nobiletin may help maintain the normal function of nerve cells by regulating the release of neurotransmitters, such as increasing acetylcholine levels. In addition, nobiletin is thought to potentially provide additional protection to nerve cells by inhibiting inflammatory responses and reducing inflammatory damage to nerve cells. 

Blood circulation improvement 

Ginkgo biloba extract  Flavonoids 24%

The flavonoids in ginkgo biloba extract can dilate blood vessels and help to increase the flexibility and elasticity of blood vessels. This can improve hemodynamics, reduce vascular resistance and promote blood flow in the body. It also inhibits platelet aggregation and helps prevent thrombosis, thereby improving blood circulation. 

Refined Fish Oils Ω-3 60%

Refined fish oil is a product rich in omega-3 polyunsaturated fatty acids, including EPA and DHA. These fatty acids have a variety of physiological effects that are beneficial to blood circulation. First of all, they show anti-inflammatory effects and reduce the adverse effects of chronic inflammation on blood vessels. Secondly, omega-3PUFA in fish oil can inhibit platelet aggregation, prevent thrombosis and improve blood fluidity. In addition, they regulate blood lipid metabolism, reduce triglyceride and LDL cholesterol levels, increase HDL cholesterol levels, and help to improve blood circulation. 

NMN 99%

Nicotinamide mononucleotide (NMN) is a compound considered to play a key role in cellular energy metabolism and biological clock regulation in the human body. First of all, the supplement of NMN may increase the content of intracellular NAD+, so as to maintain cell health, especially vascular endothelial cells, and promote good vascular function. Secondly, NMN may reduce the effect of oxidative stress on vascular endothelium by improving antioxidant capacity, which is helpful to maintain vascular health. Some studies also suggest that NMN may be related to vasodilation and indirectly participate in the regulation of vascular tension, thereby improving blood circulation. 

Phosphatidylserine 50%-80%

Phosphatidylserine (PS) is a phospholipid compound in cell membranes that may improve blood circulation. Studies have shown that PS may prevent thrombosis and help improve blood fluidity by inhibiting platelet activity and reducing platelet adhesion and aggregation. In addition, PS maintains stability and elasticity in cell membranes, which may help maintain the health of blood vessels, slow down blood vessel hardening and improve blood vessel elasticity. Although research is still ongoing, phosphatidylserine may serve as a potential supplement to help promote good blood circulation. 

Red Ginseng Extract Total Saponins 5%-10%

Red ginseng extract is believed to have multiple physiological effects on improving blood circulation, attributed to active components such as ginsenosides, polysaccharides, and saponins found in red ginseng. Firstly, ginsenosides may contribute to enhanced blood flow by dilating blood vessels and improving vascular elasticity. Secondly, polysaccharides in red ginseng may modulate the immune system, alleviating chronic inflammation and supporting overall vascular health. Additionally, saponins, including ginsenosides, are thought to inhibit platelet aggregation, reducing the risk of thrombus formation and thereby improving microcirculation. In summary, the combined actions of these components in red ginseng extract may positively impact blood circulation through various pathways. 

Improvement of learning ability

Bacopa monnieri extract Total saponins 5%-20%

The total saponinss in bacopa monnieri extract are thought to have some neuroprotective and cognitive-enhancing effects, which may help improve learning. Total saponinss are a class of natural compounds with antioxidant, anti-inflammatory, and neuroprotective properties. These properties are expected to influence the process of learning and memory through multiple mechanisms. First, Total saponinss may protect nerve cells and maintain the normal function of neurons by inhibiting oxidative stress and reducing inflammatory responses. Secondly, total saponinss are believed to affect neurotransmitter release and receptor activity, possibly modulating neurotransmission, thereby affecting learning and cognitive functions. In addition, total saponinss may also promote the growth of nerve cells and synapse formation, improve the plasticity of neural networks, and contribute to the formation of learning and memory. 

NMN 99%

Niacinamide mononucleotide (NMN) is a molecule involved in energy metabolism and cell repair and has the potential to enhance learning. NMN is converted into coenzyme NAD+ in the body, and the increase in NAD+ levels can have a positive effect on improving brain function. NAD+ not only participates in neuronal energy metabolism, but also participates in regulating intracellular redox reactions and DNA repair. Therefore, it is thought that NMN supplementation may help improve learning and promote normal function and protection of neurons. 

Pyrroquinone quinone disodium salt (PQQ) 98%

Pyrroloquinoline quinone disodium salt is a cerebral vasodilator. By dilating cerebral blood vessels, pyrroloquinoline quinone disodium salt may promote more oxygen and nutrients to reach nervous tissue, thereby increasing the metabolism and activity of neurons. It also has antioxidant and anti-inflammatory effects, helping to reduce oxidative stress and inflammatory responses in nerve cells, thereby protecting the normal function of neurons. 

Creatinine 98%

Creatinine is a molecule that stores and releases energy in muscles and is also found in brain tissue. One of its main functions is to provide additional adenosine triphosphate (ATP) to support the energy needs of cells through the synthesis of creatine phosphate. By increasing creatine phosphate levels in the brain, it improves cognitive function and learning abilities. 

Haematococcus pluvialis extract Astaxanthin 2.5%-10%

The astaxanthin contained in Haematococcus pluvialis extract has antioxidant effects, which can scavenge free radicals and reduce the damage to nerve cells caused by oxidative stress. This antioxidant effect is expected to maintain the health of brain cells and help protect and improve cognition. In addition, astaxanthin is thought to be beneficial to the cerebrovascular system, supporting learning and memory by promoting good blood circulation and increasing the supply of oxygen and nutrients to the brain. 

Saffron extract 10:1

Saffron extract can have a positive impact on improving learning ability. The main active ingredients include various carboxylated compounds, flavonoids and alkaloids, which impart antioxidant and neuroprotective properties. It scavenges free radicals through an antioxidant mechanism and reduces the damage to nerve cells caused by oxidative stress. In addition, it modulates neurotransmission by affecting neurotransmitter levels and the activity of neurotransmitter receptors, thereby improving cognition.